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Olivier Roche, MD; Francis Beby, MD; Jean-Louis Dufier, MD; Cameron F. Parsa, MD

Arch Ophthalmol. 2008;126(8):1163-1164.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In congenital glaucoma, larger degrees of corneal distention are better tolerated by the epithelium and stroma than by the Descemet membrane. A sequential ultrasound biomicroscopical (UBM) examination of the cornea helps demonstrate both the pathophysiological mechanism for the development of breaks in the Descemet membrane as well as an accompanying clefting of stromal tissue causing acute corneal hydrops. Such examinations can provide warning of impending ruptures affecting visual prognosis.

As recently demonstrated via UBM by Nakagawa and colleagues,¹ rupture of the Descemet membrane in keratoconus is also often accompanied by clefting of the stromal tissue. This leads to acute corneal opacification as well as a permanent scar after healing by secondary intention. A similar final pathway, but with minimal stromal cicatrization due to healing by primary intention, may be present in congenital glaucoma with megalocornea. Imaging with . . . [Full Text of this Article]

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