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COMMENTS AND OPINIONS
Retinal Vessels and Retinopathy of Prematurity
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Rabinowitz and colleagues1 report that wider retinal arterioles and venules in high-risk preterm infants are associated with increased risk of progression to severe retinopathy of prematurity (ROP). In adult persons with diabetes, similar findings have also been observed with regard to diabetic retinopathy, where wider retinal arterioles and venules may predict an increased risk of both the incidence and progression of retinopathy.2 This similarity supports the concept of shared mechanisms in the pathogenesis of ROP and proliferative diabetic retinopathy. The association of both diseases with venular dilation is particularly noteworthy as this sign may be a marker of endothelial dysfunction and inflammation,2 processes which may be prominent in both diseases.
An important consideration that was not addressed by the study was the effect of ocular magnification on the measurements of retinal vessel diameter. We have previously shown that eyes with high ocular magnification (ie, myopia) may appear to have spuriously . . . [Full Text of this Article]
AUTHOR INFORMATION
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ABSTRACT
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RELATED LETTER
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Arch Ophthalmol. 2008;126(6):869-870.
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