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Myopia and Axial Length Contribute to Vitreous Liquefaction and Nuclear Cataract
Nancy M. Holekamp, MD;
George J. Harocopos, MD;
Ying-Bo Shui, MD, PhD;
David C. Beebe, PhD
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In a recent article in the November 2006 issue of the Archives, Kubo et al1 report that an increase in axial length or myopia is associated with a higher grade of nuclear cataract. In the "Comment" section, they state, "The mechanism of the apparent relationship between axial length and nuclear cataract at the time of cataract surgery is unclear." They go on to suggest that "changes in vitreous circumstances caused by longer axial length may induce nuclear or other types of cataract." We would like to propose a mechanism to explain their observations. In 2004, we published an article titled "Importance of Vitreous Liquefaction in Age-Related Cataract."2 We found that the extent of vitreous liquefaction was positively correlated with the extent of nuclear opacification, even after adjusting for age. In myopic eyes, vitreous . . . [Full Text of this Article] AUTHOR INFORMATION
RELATED ARTICLE
Axial Length, Myopia, and the Severity of Lens Opacity at the Time of Cataract Surgery
E. Kubo, Y. Kumamoto, S. Tsuzuki, and Y. Akagi
Arch Ophthalmol. 2006;124(11):1586-1590.
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RELATED LETTER
Myopia and Axial Length Contribute to Vitreous Liquefaction and Nuclear Cataract—Reply
Eri Kubo, Yuko Kumamoto, Syosai Tsuzuki, and Yoshio Akagi
Arch Ophthalmol. 2008;126(5):744.
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