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Sandra M. Brown, MD; Jay C. Bradley, MD; Arshad M. Khanani, MD

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

We read with interest the article by Schmidt et al¹ regarding the effect of pupil diameter on vision-related quality of life after laser in situ keratomileusis. We have 2 objections to their methods.

First, we do not believe that pupil diameter was accurately measured. Pupil diameter is controlled by the level of rod photoreceptor activation.² Rod adaptation is not an instantaneous process. Although there may be a rapid immediate increase in pupil diameter when the lights are dimmed, additional dilation of 0.5 to 1 mm is common over 2 to 5 minutes. As pupil diameter and age are strongly correlated (Figure), we can predict one from the other: with a mean pupil diameter of 5.8 mm, we would expect the average age of the patient cohort to be approximately 60 years, not 44 years as reported. . . . [Full Text of this Article]

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