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Emine Kilic, MD, PhD; Theo Stijnen, PhD; Gre P. M. Luyten, MD, PhD

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In the October 2005 issue of the Archives, we reported that preenucleation external beam radiotherapy has a beneficial effect on survival of patients with uveal melanoma.¹ Survival after 4 years of follow-up was better in the PER group. Death due to all causes and melanoma-related death were compared between PER and EO, corrected for age and other potential confounders. Unadjusted survival curves were given as a graphical illustration. In both analyses, the risk of death was significantly lower from 4 years onward in the PER group.

Kivelä and Kujala observe that our results differ from those of the Collaborative Ocular Melanoma Study² and suggest that this might be owing to our statistical analysis being possibly biased. Unfortunately, we disagree. Kivelä and Kujala are not critical with respect to our results for death due to . . . [Full Text of this Article]

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