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A Summary of the Results From the Endophthalmitis Vitrectomy Study

Bernard H. Doft, MD

Arch Ophthalmol. 2008;126(4):554-556.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In the late 1980s, the value of pars plana vitrectomy (VIT) in the initial management of postcataract extraction-related endophthalmitis was unclear. Immediate VIT offered several theoretical advantages, but limited data from human case series had not shown that VIT conferred an advantage. In those reports, VIT had been reserved for eyes with the worst clinical manifestation. Because of severe selection bias in the reports, the role of pars plana VIT in the management of patients with endophthalmitis after cataract surgery remained uncertain.

While it was known that even the newer drugs given systemically did not reach sufficient intraocular concentrations to be effective against many common bacteria, most physicians were still administering intravenous antibiotics for postcataract-related endophthalmitis. In addition to the question of limited efficacy, their use added the risk of systemic toxicity and additional expense. While intravitreal injection of antimicrobial agents had become common for endophthalmitis, . . . [Full Text of this Article]

STUDY DESIGN


OUTCOME ASSESSMENT

RESULTS

CONCLUSIONS

AUTHOR INFORMATION
Author Affiliation: Retina Vitreous Consultants, Pittsburgh, Pennsylvania.