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  Vol. 126 No. 3, March 2008 TABLE OF CONTENTS
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Primary Clear Cell Carcinoma of the Conjunctiva

Curtis E. Margo, MD, MPH; Lewis R. Groden, MD

Arch Ophthalmol. 2008;126(3):436-438.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Clear cell carcinoma is a rare variant of squamous cell carcinoma of the skin characterized by extensive cytoplasmic hydropic change.1-2 These tumors tend to occur in the head and neck of elderly white men. Because the clear appearance of the cytoplasm is due to hydropic change rather than the accumulation of lipid, mucin, or glycogen, histochemical stain results are negative. Some of these clear cells have a "bubbled" cytoplasm and have been confused with sebaceous carcinoma.1 To our knowledge, primary clear cell carcinoma on the conjunctiva has not been reported.

Report of a Case

A 79-year-old man visited for continuation of care after changing residency. His ocular history was significant for a conjunctival tumor excised from the right eye 12 years earlier. The patient brought his medical records with him. The original pathologic interpretation was Bowen disease. After the tumor was excised, local recurrences developed . . . [Full Text of this Article]


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