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In Vivo Confocal Laser Scanning Microscopy of Corneal Nerves in Leprosy
Chen Zhao, MD, PhD;
Shasha Lu, MD, PhD;
Nadja Tajouri, MD;
Andre Dosso, MD;
Avinoam B. Safran, MD
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Leprosy has a high incidence of ocular complications, including corneal lesions, lagophthalmos, iridocyclitis, and cataract. Involvement of the trigeminal nerve is common and can result in corneal hypoesthesia. Changes in corneal nerves might be the initial ocular manifestation.1
We describe a patient in whom leprosy developed without any apparent ocular complications. In vivo confocal microscopy, however, revealed abnormal corneal nerves. Being a noninvasive imaging technique, confocal microscopy plays a valuable role in visualization of corneal nerves in that condition.
Report of a Case
A 43-year-old woman with multiple anesthetic skin lesions for 1 year was diagnosed with borderline leprosy by skin biopsy. Physical examination showed severe sensory and motor polyneuropathy, axonal and myelinic in nature. Muscle strength was preserved but severe hypoesthesia was found at the superior and inferior limbs. Using electroneuromyography, sensory assessment showed no . . . [Full Text of this Article] Comment
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