 |
 |

Participants and Methods in AREDS Report No. 8
W. Rex Hawkins, MD
 |
 |
| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
|
 |
 |
Subsequent to publication of Age-Related Eye Disease Study (AREDS) report No. 8,1 an increasing number of articles have linked age-related macular degeneration (AMD) and cataract surgery.2-5 The studies have relevance to AREDS report No. 8 for which cataract surgery was not considered a reason for participant exclusion. The AREDS Coordinating Center acknowledged, in correspondence with me (Roy C. Milton, PhD, written communication, October 19, 2006), that 161 participants were unilaterally pseudophakic and that another 507 required cataract surgery during the study. Such information was not included in the published article.
The recent articles suggest that cataract surgery should be an indication for exclusion in AMD therapy trials such as that described in AREDS report No. 8. I question whether the AREDS investigators now wonder whether the selection process was flawed with respect to the inclusion of eyes that underwent cataract surgery and whether they have considered . . . [Full Text of this Article] AUTHOR INFORMATION
CiteULike Connotea Del.icio.us Digg Reddit Technorati Twitter
What's this?
RELATED LETTER
Participants and Methods in AREDS Report No. 8—Reply
Roy C. Milton, Traci E. Clemons, and Emily Y. Chew
Arch Ophthalmol. 2008;126(1):147.
EXTRACT
| FULL TEXT
RELATED ARTICLES
The Association of Cataract and Cataract Surgery With the Long-term Incidence of Age-Related Maculopathy: The Beaver Dam Eye Study
Ronald Klein, Barbara E. K. Klein, Tien Y. Wong, Sandra C. Tomany, and Karen J. Cruickshanks
Arch Ophthalmol. 2002;120(11):1551-1558.
ABSTRACT
| FULL TEXT
A Randomized, Placebo-Controlled, Clinical Trial of High-Dose Supplementation With Vitamins C and E, Beta Carotene, and Zinc for Age-Related Macular Degeneration and Vision Loss: AREDS Report No. 8
Age-Related Eye Disease Study Research Group
Arch Ophthalmol. 2001;119(10):1417-1436.
ABSTRACT
| FULL TEXT
|