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ATul Jain, MD; Peter Egbert, MD; Timothy J. McCulley, MD; Mark S. Blumenkranz, MD; Darius M. Moshfeghi, MD

Arch Ophthalmol. 2007;125(9):1286-1289.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Scedosporium apiospermum is the asexual form of Pseudallescheria boydii, a ubiquitous saprophytic filamentous fungus.¹ Neutropenia predisposes patients to infection with this organism.² Endogenous endophthalmitis from S apiospermum is a rare but grave sequela.³

We present 3 cases of endogenous S apiospermum endophthalmitis and histopathologic findings.

Report of Cases

Case 1

A 59-year-old woman with pre–B-cell acute lymphocytic leukemia developed neutropenia (absolute neutrophil count, <100 cells/mm³) and blurred vision in her left eye. She received intravenous piperacillin sodium–tazobactam sodium, amphotericin B, vancomycin hydrochloride, acyclovir sodium, and sulfamethoxazole-trimethoprim. Her vision deteriorated, and skin lesions appeared on the right arm and left hip. Results of peripheral blood and cutaneous and pulmonary biopsy cultures were negative.

Visual acuity was 20/20 OD and 20/400 OS, with central scotoma and pain in the left eye. There was vitritis with preretinal exudation . . . [Full Text of this Article]

Case 2

Case 3

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