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  Vol. 125 No. 7, July 2007 TABLE OF CONTENTS
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  Clinicopathologic Reports, Case Reports, and Small Case Series
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 •External Eye Disease
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 •Melanoma
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Eyelid Melanoma With Negative Sentinel Lymph Node Biopsy and Perineural Spread

Mary E. Turell, BS; Devron H. Char, MD

Arch Ophthalmol. 2007;125(7):983-984.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Evaluation and treatment of periocular melanomas can be difficult. Sentinel lymph node biopsy, introduced by Morton et al,1 is a mode of early detection of regional lymph node metastasis for many variants of solid tumors. Prognostically, these data correlate more closely with melanoma-related mortality than other histologic data.2 Perineural invasion of cutaneous eyelid melanoma is uncommon; neither Dr Char nor William Hoyt, MD (oral communication, May 2005) have seen a case without marked sensory asymmetry. Our case provides a cautionary note regarding both sentinel lymph node biopsy and physical findings associated with perineural invasion.

Report of a Case

A 20-year-old woman had delayed diagnosis of a left medial eyelid malignant melanoma. The patient was examined elsewhere at age 14 years for a red, acneiform papule and was followed up for 6 years. During the past year, she experienced periocular shooting pain 1 to 2 times daily . . . [Full Text of this Article]


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