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Scleritis and Peripheral Ulcerative Keratitis With Hepatitis C Virus–Related Cryoglobulinemia
Sanjay R. Kedhar, MD;
Marie-Lyne Belair, MD;
Albert S. Jun, MD, PhD;
Mark Sulkowski, MD;
Jennifer E. Thorne, MD, PhD
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In patients with peripheral ulcerative keratopathy (PUK), concomitant scleritis is highly correlated with systemic disease (72.3% of patients), typically systemic vasculitis, rheumatoid arthritis–related vasculitis, or systemic lupus erythematosus–related vasculitis.1 We describe a patient with necrotizing scleritis and PUK associated with hepatitis C virus (HCV)–related cryoglobulinemia. To our knowledge, this is the first description of this association.
Case Report
A 49-year-old woman was referred to our service for necrotizing scleritis and PUK. Her medical history was significant for hepatitis 20 years earlier and a 17-year history of recurrent corneal ulceration thought to be secondary to rosacea. In 2004, she had a corneal perforation in the right eye that was treated with patch grafting and doxycycline.
At the initial examination, visual acuity was 20/16 OU. Slitlamp examination revealed a well-healed scleral patch graft in . . . [Full Text of this Article]
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