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Rhino-orbital Mucormycosis Causing Cavernous Sinus and Internal Carotid Thrombosis Treated With Posaconazole
Christopher D. Gelston, MD;
Vikram D. Durairaj, MD;
Eric A. F. Simoes, MD
Arch Ophthalmol. 2007;125(6):848-849.
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Rhino-orbital mucormycosis usually leads to acutely fatal fungal infections in immunocompromised patients through central nervous system invasion or vascular thrombosis. Historically, untreated orbital mucormycosis has a survival rate of 24%, but the recent combination of surgical debridement and amphotericin B has improved patient survival to 85%.1-2 Ophthalmologists are often involved in making medical and surgical decisions in these complex cases; therefore, it is important to be aware of advances in the management of this disorder. We describe herein a case of rhino-orbital mucormycosis and cavernous sinus and internal carotid thrombosis treated with posaconazole after the failure of initial treatment with surgical debridement and amphotericin B.
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A 7-year-old girl with poorly controlled diabetes was seen at a nearby hospital for a 2-day history of left eyelid swelling and pain. After 2 days of treatment with intravenous ceftriaxone sodium . . . [Full Text of this Article]
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Use of Radiopaque Intraorbital Catheter in the Treatment of Sino-Orbito-Cranial Mucormycosis
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Arch Ophthalmol 2007;125:1714-1715.
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