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Minocycline for the Treatment of Ocular and Ocular Adnexal Sarcoidosis
D. J. John Park, MD;
John J. Woog, MD;
Jose S. Pulido, MD;
J. Douglas Cameron, MD
Arch Ophthalmol. 2007;125(5):705-709.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Sarcoidosis is a chronic systemic inflammatory disorder characterized by noncaseating granulomas. Although almost any organ can be affected, common sites of involvement include the skin, lungs, lymph node, eye, and ocular adnexa. Corticosteroids have remained the first-line therapy since their introduction in the 1950s.1 However, because of the significant adverse effects associated with chronic corticosteroid use, treatment is typically reserved for those with severe visceral involvement or refractory ocular and ocular adnexal involvement.
A number of steroid-sparing agents have been used with varying success in the treatment of chronic sarcoidosis. Bachelez et al2 reported clinical response in 10 of 12 patients with cutaneous sarcoidosis treated with minocycline. We describe herein the first reported case of ocular, ocular adnexal, and systemic sarcoidosis treated with minocycline.
Report of a Case
A 41-year-old white woman was referred with a 3-week . . . [Full Text of this Article] Comment
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