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  Vol. 125 No. 4, April 2007 TABLE OF CONTENTS
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Visualization of Lipofuscin Accumulation in Stargardt Macular Dystrophy by High-Resolution Fourier-Domain Optical Coherence Tomography

Christina Gerth, MD; Robert J. Zawadzki, PhD; Stacey S. Choi, PhD; John L. Keltner, MD; Susanna S. Park, MD, PhD; John S. Werner, PhD

Arch Ophthalmol. 2007;125(4):575.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

A 15-year-old patient was diagnosed with Stargardt macular dystrophy based on maculopathy (Figure 1) and abnormal multifocal electroretinographic responses. Retinal images were obtained with high-speed (up to 18 000 A-scans/s; 18 frames/s; 1000 lines/frame), high-resolution (axial ~ 4.5 µm; lateral 10-15 µm) Fourier-domain optical coherence tomography (FDOCT) (constructed at University of California, Davis).1-2 The FDOCT revealed well-demarcated oval to round "bumps" within the retinal pigment epithelial layer extending from subfoveal to 5° extrafoveal (Figure 2A). The outer nuclear layer was not detectable in this area when compared with an age-matched control (Figure 2B).


 
Figure appears in full text version.
Figure 1. Fundus photograph and fluorescein angiography (FA) of the left eye. A, Perimacular yellowish flecks and blunting of the foveal reflex are seen (visual acuity: 20/150 with extrafoveal fixation). . . . [Full Text of this Article]


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