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  Vol. 125 No. 4, April 2007 TABLE OF CONTENTS
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  Clinicopathologic Reports, Case Reports, and Small Case Series
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Acetazolamide in the Treatment of X-Linked Retinoschisis Maculopathy

Mehdi Ghajarnia, MD; Michael B. Gorin, MD

Arch Ophthalmol. 2007;125(4):571-573.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Macular schisis cavities observed in patients with X-linked retinoschisis are not associated with leakage on fluorescein angiogram as seen in other forms of cystoid macular edema. We report a case in which a young patient with this condition showed a reproducible clinical response to oral acetazolamide therapy with normalization of both macular anatomy and visual acuity.

Report of a Case

An 8-year-old boy was evaluated for reduced central vision. At age 4 years, pigmentary changes were noted in his left fundus, and he had been treated for amblyopia with hyperopic correction and patching. Best-corrected visual acuities in each eye had varied between 20/60 and 20/30.

He had no other significant medical history and received no medications, and the family ophthalmic history was positive only for amblyopia in a great-uncle. Snellen visual acuities were OU 20/70 with equally reactive pupils. Dilated examination showed granular midperipheral retinal pigment epithelium . . . [Full Text of this Article]


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