JAMA
An Outbreak of Fusarium Keratitis Associated With Contact Lens Wear in Singapore
Context: Fungal keratitis is a potentially blinding condition that is rarely seen with contact lens wear.
Objective: To describe a nationwide outbreak of fungal keratitis caused by Fusarium species among contact lens wearers in Singapore.
Design, Setting, and Patients: Nationwide, hospital-based case series. All cases of fungal keratitis among contact lens wearers in all ophthalmology departments in Singapore were reviewed along with the charts of all contact lens wearers with culture-proven fungal keratitis from March 2005 through May 2006. A standardized telephone interview was conducted to obtain additional clinical information.
Main Outcome Measure: Diagnosis of Fusarium keratitis associated with contact lens wear.
Results: During the study period, 66 patients (68 affected eyes) were diagnosed with Fusarium keratitis associated with contact lens wear; the estimated annual national incidence is 2.35 cases per 10 000 contact lens wearers (95% confidence . . . [Full Text of this Article]