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Arch Ophthalmol. 2006;124(9):1339-1340.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

JAMA

Dietary Intake of Antioxidants and Risk of Age-Related Macular Degeneration

Redmer van Leeuwen, MD, PhD; Sharmila Boekhoorn, MD; Johannes R. Vingerling, MD, PhD; Jacqueline C. M. Witteman, PhD; Caroline C. W. Klaver, MD, PhD; Albert Hofman, MD, PhD; Paulus T. V. M. de Jong, MD, PhD

Context:  Age-related macular degeneration (AMD) is the most prevalent cause of irreversible blindness in developed countries. Recently, high-dose supplementation with beta carotene, vitamins C and E, and zinc was shown to slow the progression of AMD.

Objective:  To investigate whether regular dietary intake of antioxidants is associated with a lower risk of incident AMD.

Design:  Dietary intake was assessed at baseline in the Rotterdam Study (1990-1993) using a semiquantitative food frequency questionnaire. Incident AMD until final follow-up in 2004 was determined by grading fundus color transparencies in a masked way according to the International Classification and Grading System.

Setting:  Population-based cohort of all . . . [Full Text of this Article]