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In reply

We are in essential agreement with the comments by Drs Kivelä and Summanen, and we basically concur with their interpretation that any malignant neoplasm of the anterior segment of the eye may become retroinvasive in the proper environment.

We sincerely thank Drs Kivelä and Summanen for their thoughtful comments regarding the important concept that they designate as retroinvasive phenotype, which also applies to melanomas of the ciliary body.

AUTHOR INFORMATION
Correspondence: Dr Font, Ophthalmic Pathology Laboratory, Cullen Eye Institute, Baylor College of Medicine, 6565 Fannin, NC-205, Houston, TX 77030 (rfont@bcm.tmc.edu).

Financial Disclosure: None reported.

Ramon L. Font, MD; Kirtee Rishi, MD

Arch Ophthalmol. 2006;124:1067.

RELATED LETTER

Possible Shared Pathogenesis of the Retinoinvasive Phenotype of Malignant Medulloepithelioma and Malignant Melanoma of the Ciliary Body
Tero Kivelä and Paula Summanen
Arch Ophthalmol. 2006;124(7):1066.
EXTRACT | FULL TEXT  

RELATED ARTICLE

Diffuse Retinal Involvement in Malignant Nonteratoid Medulloepithelioma of Ciliary Body in an Adult
Ramon L. Font and Kirtee Rishi
Arch Ophthalmol. 2005;123(8):1136-1138.
EXTRACT | FULL TEXT