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Acute Posterior Multifocal Placoid Pigment Epitheliopathy With Cerebral Vasculitis: A Multisystem Granulomatous Disease
Arch Ophthalmol. 2006;124:910-913.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Typically, acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is seen along with acute binocular visual disturbance (ie, visual blurring, metamorphopsia, or scotomas) in young adults of whom approximately one third experience a flulike illness at onset.1 The clinical course is usually self-limited, with remarkable visual recovery. A few cases with cerebral vasculitis or meningoencephalitis have been reported.2-5 Although circumstantial evidence for a choroidal vasculitis is gathering, the exact pathological origin of APMPPE remains unknown. Herein we report a case of APMPP-associated cerebral vasculitis with angiographic, radiologic, and, to our knowledge, for the first time in the literature autopsy findings that include both ocular and cerebral histopathological descriptions.
Report of a Case
Clinical History. A 23-year-old white man developed acute loss of vision in the right eye. There was no history of a flulike illness and his medical history only denoted resection of nasal polyps. On examination visual acuity was confined to perception of . . . [Full Text of this Article] Comment
AUTHOR INFORMATION
Joeke Jurjen de Vries, MD;
Wilfred F. A. den Dunnen, MD, PhD;
Ed A. Timmerman, MD;
Inge G. Kruithof, MD;
Jacques De Keyser, MD, PhD
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