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  Vol. 124 No. 6, June 2006 TABLE OF CONTENTS
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Acute Posterior Multifocal Placoid Pigment Epitheliopathy With Cerebral Vasculitis: A Multisystem Granulomatous Disease

Arch Ophthalmol. 2006;124:910-913.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Typically, acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is seen along with acute binocular visual disturbance (ie, visual blurring, metamorphopsia, or scotomas) in young adults of whom approximately one third experience a flulike illness at onset.1 The clinical course is usually self-limited, with remarkable visual recovery. A few cases with cerebral vasculitis or meningoencephalitis have been reported.2-5 Although circumstantial evidence for a choroidal vasculitis is gathering, the exact pathological origin of APMPPE remains unknown. Herein we report a case of APMPP-associated cerebral vasculitis with angiographic, radiologic, and, to our knowledge, for the first time in the literature autopsy findings that include both ocular and cerebral histopathological descriptions.

Report of a Case

Clinical History. A 23-year-old white man developed acute loss of vision in the right eye. There was no history of a flulike illness and his medical history only denoted resection of nasal polyps. On examination visual acuity was confined to perception of . . . [Full Text of this Article]


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AUTHOR INFORMATION
Joeke Jurjen de Vries, MD; Wilfred F. A. den Dunnen, MD, PhD; Ed A. Timmerman, MD; Inge G. Kruithof, MD; Jacques De Keyser, MD, PhD







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