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  Vol. 124 No. 5, May 2006 TABLE OF CONTENTS
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  Clinicopathologic Reports, Case Reports, and Small Case Series
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Optical Coherence Tomography Demonstration of Macular Infarction in Sickle Cell Retinopathy

Arch Ophthalmol. 2006;124:746-747.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Sickle cell retinopathy is caused by retinal ischemia secondary to the sickling of red blood cells in retinal arterioles, which supply nutrients to the ganglion cell layer, inner nuclear layer, and Muellerian glia of the retina. Macular infarction due to sickle cell disease has been documented using fluorescein angiography, electroretinography, and histopathologic examination.1-3 However, optical coherence tomography (OCT) of sickle cell retinopathy has, to our knowledge, never previously been reported. We report a case of macular atrophy secondary to retinal arteriolar occlusion in a patient with sickle cell disease, documented by standard-resolution OCT and ultra-high-resolution OCT, a new imaging technology capable of 2- to 3-µm resolution in the axial direction4 compared with 10 µm with standard-resolution OCT.5

Report of a Case

A 26-year-old man with sickle cell disease (HbSS) went to the emergency department during an acute sickle cell crisis and was admitted to the medical intensive care unit with myocardial infarction, acute renal . . . [Full Text of this Article]


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AUTHOR INFORMATION
Andre J. Witkin, BS; Adam H. Rogers, MD; Tony H. Ko, MS; James G. Fujimoto, PhD; Joel S. Schuman, MD; Jay S. Duker, MD



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