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Report of a Conjunctival Myxoma Case and Review of the Literature
Arch Ophthalmol. 2006;124:735-738.
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Myxoma is a benign soft tissue tumor that presumably derives from primitive mesenchyme. It is characterized histopathologically by abundant mucoid material, a loose meshwork of reticulin fibers, and relatively small numbers of spindle- and stellate-shaped cells.1 The stromal matrix is rich in glucosaminoglycans and hyaluronic acid, and it is sparse in collagen and vascular structures.1 Myxoma can appear as localized disease or as a component of Carney complex, which includes cutaneous and cardiac myxomas, multiple pigmented lesions, and endocrine overactivity, leading to significant morbidity and mortality.2 Myxoma is the most common primary cardiac tumor. This tumor can arise in the skeletal muscle, bone, skin, genitourinary system, gastrointestinal tract, and nasal sinuses.3 It can rarely involve ocular structures and has been recognized in the eyelid, orbit, and conjunctiva.4-6
In a review of 2455 conjunctival lesions submitted to an ophthalmic pathology laboratory, only 4 patients (0.002%) were found to have conjunctival myxoma.4 . . . [Full Text of this Article] Report of a Case
Comment
AUTHOR INFORMATION
Hakan Demirci, MD;
Carol L. Shields, MD;
Ralph C. Eagle, Jr, MD;
Jerry A. Shields, MD
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