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We enjoyed the article by Patel et al¹ entitled "Histopathology of Radial Keratotomy" in the January issue of the ARCHIVES that described a case of severe central subepithelial fibrosis following radial keratotomy. We would like to compliment the authors on bringing this rare but potentially visually disabling complication of radial keratotomy to the attention of our colleagues. We also appreciate the reference to our articles describing the use of topical mitomycin C (MMC) for the treatment of this condition.^2-3

We would like to note that the original patient who was treated by us with MMC was very similar, with post–radial keratotomy with central subepithelial fibrosis and a best-corrected visual acuity of 20/200. Since the initial article,² the use of MMC in refractive surgery, particularly in association with surface ablation in "high-risk" cases (such as this), has become increasingly popular.^4-6 We believe that patients such as the one you described . . . [Full Text of this Article]

AUTHOR INFORMATION
Randy J. Epstein, MD; Parag A. Majmudar, MD

RELATED ARTICLE

Histopathology of Radial Keratotomy
Sarit M. Patel, Rachel A. Tesser, Daniel M. Albert, and Christopher R. Croasdale
Arch Ophthalmol. 2005;123(1):104-105.
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