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Edward W. Lee, MD; William F. Mieler, MD

Arch Ophthalmol. 2006;124:1656-1658.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Hemophagocytic syndrome is a rare disease characterized by fevers, hepatosplenomegaly, and pancytopenia. Additionally, there is increased proliferation and activation of macrophages, with hemophagocytosis seen histologically in the liver, spleen, and bone.¹ Only 3 case reports^2-4 of retinal findings associated with hemophagocytic syndrome have appeared in the literature. Two reports^3-4 describe retinal hemorrhages, disc edema, and perivenous white patches, and the other² describes acute posterior multifocal placoid pigment epitheliopathy–like findings. We report a case of hemophagocytic syndrome with ocular findings that, to our knowledge, have not been previously described in the literature.

Report of a Case

A 31-year-old African American woman admitted for fevers, 18-kg weight loss, hepatosplenomegaly, and ascites over a 6-month period was referred to the Department of Ophthalmology, University of Chicago, Chicago, Ill, for bilateral visual blurring of 1 week's duration. The patient was being treated with intravenous ceftazidime, fluconazole, and acyclovir for a . . . [Full Text of this Article]

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