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Optic Nerve Structure in Healthy Subjects
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We read with interest the recent article by Racette et al1 on the differences in optic nerve structure between the healthy eyes of blacks and whites. They describe several significant findings, but we think 2 deserve particular attention: blacks have larger optic disc areas, as measured by the Heidelberg Retina Tomograph, and a thicker retinal nerve fiber layer (RNFL) in the superior and inferior quadrants, as measured by optical coherence tomography (OCT). According to the authors, the latter result, which may have important consequences from a clinical point of view, seems to contradict previous studies performed by scanning laser polarimetry that demonstrated a thinner RNFL in blacks.2-3 We suggest, as a possible explanation for this apparent discrepancy, that there is an artifact in the OCT measurement consequent to the relationship between the RNFL thickness and the optic nerve head (ONH) size.4 Standard OCT protocol measures the RNFL by means of . . . [Full Text of this Article] AUTHOR INFORMATION
Giacomo Savini, MD;
Maurizio Zannini, MD;
Valerio Carelli, MD, PhD;
Alfredo A. Sadun, MD, PhD;
Fred N. Ross-Cisneros, MD;
Piero Barboni, MD
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Optic Nerve Structure in Healthy SubjectsReply
Lyne Racette, Catherine Boden, Shannon L. Kleinhandler, Christopher A. Girkin, Jeffrey M. Liebmann, Linda M. Zangwill, Felipe A. Medeiros, Christopher Bowd, Robert N. Weinreb, M. Roy Wilson, and Pamela A. Sample
Arch Ophthalmol. 2006;124(10):1508-1509.
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Differences in Visual Function and Optic Nerve Structure Between Healthy Eyes of Blacks and Whites
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Arch Ophthalmol. 2005;123(11):1547-1553.
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