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Histopathology and Ultrastructure of Human Corneas After Amniotic Membrane Transplantation
Berthold Seitz, MD, FEBO;
Miklós D. Resch, MD;
Ursula Schlötzer-Schrehardt, PhD;
Carmen Hofmann-Rummelt, BS;
Renate Sauer, MD;
Friedrich E. Kruse, MD
Arch Ophthalmol. 2006;124:1487-1490.
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In recent years, amniotic membrane (AM) transplantation (AMT) has been used increasingly to treat various types of ocular surface pathologies.1 Diverse techniques of AMT have been proposed for corneal diseases. One or more layers of AM can be used as a patch, graft, or sandwich (combination of 1 graft and a patch)2-3 (Figure 1). Despite a growing body of literature on clinical applications of AM, little is known about the pathology of human corneas after AMT.4-5 We offer histopathological, immunohistochemical, and ultrastructural evidence of the corneal epithelial (CE) growth patterns in relation to the AM.
Figure appears in full text version.
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Figure 1. Schematic drawings of various techniques of amniotic membrane (AM) transplantation (in each instance the AM is used epithelial side up). A, Patch onlay, used for corneal diseases with nonhealing epithelial . . . [Full Text of this Article]
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Methods
Report of Cases Case 1Case 2 Case 3 Comment
AUTHOR INFORMATION
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