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Unilateral Retinal Nerve Fiber Myelination With Contralateral Amblyopia
Arch Ophthalmol. 2006;124:128-130.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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During normal prenatal development, retinal ganglion axon myelination starts centrally in the lateral geniculate body and proceeds anteriorly to the optic tracts, chiasm, and nerves. This process of myelination normally terminates shortly after birth at the level of the lamina cribrosa; however, occasionally myelination occurs in the retinal nerve fiber layer.1 Although generally considered to be a benign funduscopic finding, myelinated nerves have been associated with visual field defects, severe myopia, amblyopia, and strabismus.2-3
To our knowledge, all of the reported cases of amblyopia have occurred in the eye affected with myelinated fibers. In this article, we describe 2 patients with unilateral myelinated nerve fibers who had amblyopia in the eye not affected with nerve fiber layer myelination. We believe that these cases shed light on the causes of reduced visual acuity in patients with retinal nerve fiber layer myelination.
Report of Cases
Case 1. A 5-year-old boy was referred for evaluation of . . . [Full Text of this Article]
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AUTHOR INFORMATION
Mark S. Ruttum, MD;
Jed Poll, MD
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