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Arch Ophthalmol. 2005;123(7):1002.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

New England Journal of Medicine

Corneal Reconstruction With Tissue-Engineered Cell Sheets Composed of Autologous Oral Mucosal Epithelium: A New Approach to Ocular Surface Reconstruction in Bilateral Limbal Stem Cell Deficiency

Kohji Nishida, MD, PhD; Masayuki Yamato, PhD; Yasutaka Hayashida, MD; Katsuhiko Watanabe, MSc; Kazuaki Yamamoto, MSc; Eijiro Adachi, MD, PhD; Shigeru Nagai, MSc; Akihiko Kikuchi, PhD; Naoyuki Maeda, MD, PhD; Hitoshi Watanabe, MD, PhD; Teruo Okano, PhD; Yasuo Tano, MD, PhD

Background:  Ocular trauma or disease may lead to severe corneal opacification and, consequently, severe loss of vision as a result of complete loss of corneal epithelial stem cells. Transplantation of autologous corneal stem-cell sources is an alternative to allograft transplantation and does not require immunosuppression, but it is not possible in many cases in which bilateral disease produces total corneal stem-cell deficiency in both eyes. We studied the use of autologous oral mucosal epithelial cells as a source of . . . [Full Text of this Article]

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ABSTRACT | FULL TEXT