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Arch Ophthalmol. 2005;123:856-863.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Retinal astrocytic hamartoma is the best-known ocular manifestation of tuberous sclerosis complex (TSC).^1-2 It is generally a sessile or slightly elevated lesion in the nerve fiber layer of the retina, but it can have several clinical variations. It can be unilateral, bilateral, solitary, multifocal, transparent, opaque, noncalcified, or calcified.^1-2 Retinal astrocytic hamartoma in association with TSC generally is considered to be a relatively stationary lesion that has little potential for aggressive behavior.^1-5 In rare instances, however, a retinal astrocytic hamartoma can show progressive growth and cause severe local complications. We report the clinical course and histopathologic findings in 4 patients with TSC, each of whom developed progressive growth of a juxtapapillary astrocytic hamartoma that caused secondary retinal detachment and neovascular glaucoma, necessitating enucleation of the affected eye.

Methods

The clinical records and histopathologic findings were reviewed and summarized on 4 patients with TSC who underwent enucleation of 1 eye because of . . . [Full Text of this Article]

Results

Pathologic Findings

Comment

AUTHOR INFORMATION
Jerry A. Shields, MD; Ralph C. Eagle, Jr, MD; Carol L. Shields, MD; Brian P. Marr, MD

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