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Systemic Antibiotics for Communitywide Trachoma Control
Arch Ophthalmol. 2005;123(5):687-688.
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New England Journal of Medicine
Mass Treatment With Single-Dose Azithromycin for Trachoma
Anthony W. Solomon, MB, BS, PhD; Martin J. Holland, PhD; Neal D. E. Alexander, PhD; Patrick A. Massae, DCEH; Aura Aguirre, PhD; Angels Natividad-Sancho, MSc; Sandra Molina, MSc; Salesia Safari, MD; John F. Shao, MD, PhD; Paul Courtright, DrPH; Rosanna W. Peeling, PhD; Sheila K. West, PhD; Robin L. Bailey, FRCP, PhD; Allen Foster, FRCS, FRCOphth; David C. W. Mabey, DM, FRCP
Background: Trachoma, caused by repeated ocular infection with Chlamydia trachomatis, is an important cause of blindness. Current recommended dosing intervals for mass azithromycin treatment for trachoma are based on a mathematical model.
Methods: We collected conjunctival swabs for quantitative polymerase-chain-reaction assay of C. trachomatis before and 2, 6, 12, 18, and 24 months after mass treatment with azithromycin in a Tanzanian community in which trachoma was endemic. For ethical reasons, at 6, 12, and 18 . . . [Full Text of this Article]
AUTHOR INFORMATION
Alfred Sommer, MD, MHS
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Frequency of Antibiotic Coverage and Elimination of Blinding Trachoma
Sommer
Arch Ophthalmol 2008;126:1000-1001.
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