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Allow me to add another perspective to the thoughtful editorial "Does Sex Matter in Glaucoma?"¹ which stated, "There is no clear consensus in the ophthalmic literature regarding the association of sex and glaucoma." While the editorial speaks of "glaucomatous disease" and "glaucoma" in general, it perhaps addresses, without saying so, the issue of primary open-angle glaucoma alone. For the evidence is solid when it comes to anatomic gender differences and their implication for the prevalence and pathogenesis of ocular hypertension and primary angle-closure glaucoma.

In a recent study of 513 eyes,² we found that women’s eyes were on average more than 1 mm shorter than men’s. Their average applanation tonometric readings were more than half a unit higher. In addition, because of emmetropization,³ women’s lens and corneal curvatures are steeper, and the latter also results in higher tonometric readings.^4-5 Women are therefore more likely than men to fall into the . . . [Full Text of this Article]

AUTHOR INFORMATION
Harry H. Mark, MD, FACS