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Treatment of Recurrent Corneal Erosion With Substance P–Derived Peptide and Insulin-like Growth Factor I
Arch Ophthalmol. 2005;123:1445-1447.
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A 32-year-old woman was referred to us in September 2002. In February 1999, she experienced a traumatic corneal erosion in her right eye. After initial corneal healing, she developed several episodes of ocular pain, photophobia, and profuse tearing upon awakening. She visited an ophthalmologist and the diagnosis of recurrent corneal erosion (RCE) was made. She was treated with eye drops and ointments containing 5% sodium chloride for several months, but the epithelial erosion did not heal. She visited another ophthalmologist who added a therapeutic contact lens to her treatment, but there was no improvement.
On her initial visit to us, her visual acuity was 20/30 and she had experienced 26 RCE episodes. An epithelial defect with loosely adherent and elevated epithelium was evident in her right eye. Epithelial basement membrane dystrophy, ocular rosacea, and diabetes mellitus were excluded. Confocal microscopy showed islets of highly reflective cells with presumed intracellular deposits . . . [Full Text of this Article]
AUTHOR INFORMATION
Jose M. Benitez-del-Castillo, MD, PhD;
Serafín Rodríguez-Bayo, MD, PhD;
Eva Fontan-Rivas, MD;
Jose M. Martinez-de-la-Casa, MD, PhD;
Julian Garcia-Sanchez, MD, PhD
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