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Giant Cell Angiofibroma of the Ocular Adnexae
Arch Ophthalmol. 2005;123:1438-1443.
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Giant cell angiofibroma (GCA) is a rare tumor. It was originally described by Dei Tos et al1 as an orbital tumor. These tumors are characterized by a patternless proliferation of spindle cells, multinucleated giant cells, and pseudovascular spaces. The stroma is collagenized or myxoid. Tumor cells stain positively for CD34 and vimentin. The morphologic appearance is similar to that of solitary fibrous tumor (SFT) and giant cell fibroblastoma (GCF). In fact, Guillou et al2 have advocated that GCA is likely a giant cell-rich variant of SFT.
In this article, a case of GCA of the conjunctiva is described. The clinicopathologic features of this tumor are reviewed.
Report of a Case
A 24-year-old man had a 12-month history of an inferior conjunctival lesion of the right eye. The lesion was painless and had not changed in size, color, or texture. Fullness of the right lower eyelid region was present (Figure 1A). The lesion . . . [Full Text of this Article] Results
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AUTHOR INFORMATION
Alice Song, MD;
Nasreen Syed, MD;
Patricia A. Kirby, MD;
Keith D. Carter, MD
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