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Sequestration and Late Activation of Lenticular Candida Abscess in Premature Infants
Arch Ophthalmol. 2004;122:1393-1395.
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Endogenous intraocular Candida infection typically presents as chorioretinitis with varying degrees of vitreous infiltration and inflammation. In patients with concurrent or recent candidemia, intralenticular fungal abscess is rare but has been reported previously in premature infants.1-3 We report a fourth and fifth case of this unusual syndrome, emphasizing its clinical signs, peculiar clinical course, and the possibility of a good visual outcome with appropriate therapy.
Report of Cases
Case 1. An infant girl was born at 24 weeks postconceptual age and weighed 750 g. The postnatal course was complicated by bronchopulmonary dysplasia, apnea, patent ductus arteriosis, anemia, hypertension, gastrointestinal reflux, and subclinical necrotizing enterocolitis. The patient also developed candidemia with blood and urine cultures positive for organisms at 3 weeks of age. She was found to have a large right atrial mass compatible with fungus that showed evidence of inferior vena cava obstruction. She was treated with amphotericin B and fluconazole for a . . . [Full Text of this Article]
Comment
Rita Singh-Parikshak, MD;
Erick D. Bothun, MD;
Roseanne Superstein, MD;
Monte Del Monte, MD;
Steven Archer, MD;
Mark W. Johnson, MD
Correspondence: Dr Singh-Parikshak, Simpson Eye Associates, 650 Springhill Ring Rd, West Dundee, IL 60118 (ritasing10@hotmail.com).
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