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Allergic Fungal Sinusitis With Unilateral Eye Involvement
Arch Ophthalmol. 2004;122:1390-1393.
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We describe 2 patients with ocular signs and symptoms who were subsequently diagnosed as having allergic fungal sinusitis (AFS). This disease is characterized primarily by chronic rhinosinusitis, nasal polyposis, allergic mucin, and the presence of fungal organisms according to a culture and/or histologic examination.1 Clinical features are those associated with chronic rhinosinusitis, which include facial pressure, nasal obstruction, and rhinorrhea.2 Proptosis, ptosis, and diplopia are the most common ocular symptoms; however, these conditions rarely represent the initial manifestation of the disease. The nasal mucus specimens of patients with AFS are designated as allergic mucin because of the abundance of eosinophils and their degradation products within the mucus.1 Although standardized treatment for AFS is not well defined, surgical debridement and systemic corticosteroid therapy are commonly recommended.
The typical patient with AFS is young and immunocompetent with a history of asthma or atopy.2 Orbital involvement in AFS is caused by the direct . . . [Full Text of this Article] Report of Cases
Comment
Blake N. Geren, BS;
Harry H. Brown, MD;
H. Graves Hearnsberger III, MD;
Christopher T. Westfall, MD
Correspondence: Dr Westfall, Department of Ophthalmology, Mail Slot 523, 4301 W Markham St, Little Rock, AR 72205-7199 (westfallchristophert@uams.edu).
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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Allergic Fungal Sinusitis With Subperiosteal Orbital Abscess
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Arch Ophthalmol 2005;123:1281-1282.
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