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Arch Ophthalmol. 2004;122:1383-1390.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

We report the histopathologic features of a successfully treated serous retinal pigment epithelial detachment (RPED) with accompanying choroidal neovascularization (CNV) in a 74-year-old woman with age-related macular degeneration (AMD). These findings were correlated with antemortem fluorescein and indocyanine green (ICG) angiographic studies. Histopathologic studies showed that the serous RPED represented a separation of the retinal pigment epithelium (RPE) and its basal lamina from the remainder of the Bruch membrane with no intervening CNV. Laser photocoagulation had successfully closed the accompanying sub-RPE (Gass type 1, presumed intra-Bruch) choroidal neovascular membrane. The RPED resolved, leaving a fairly well-preserved RPE monolayer, which reapposed the Bruch membrane, allowing retention of very good vision for 21 months. Additionally, in an area of drusen resorption, only small calcific deposits remained and there was no remaining basal laminar deposit.

Only a limited number of previous reports describe histopathologic correlative studies with recent fluorescein and ICG angiography in . . . [Full Text of this Article]

Report of a Case


Results

Comment
Andreas K. Lauer, MD; Jonathan Yoken, MD; Michael L. Klein, MD; David J. Wilson, MD
Portland, Ore

Correspondence: Dr Lauer, Casey Eye Institute, Oregon Health and Science University, 3375 SW Terwilliger Blvd, Portland, OR 97239.