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Bilateral Serous Retinal Detachment Due to Protein-Losing Enteropathy
Arch Ophthalmol. 2004;122:1067-1070.
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Protein-losing enteropathy (PLE) refers to a group of disorders causing hypoproteinemia and edema in the absence of proteinuria or defects in protein synthesis.1 It is characterized by increased protein loss in the gastrointestinal tract and is commonly suggested by the presence of peripheral edema and low serum albumin and globulin levels, in the absence of renal and hepatic disease. We describe an unusual patient with a corticosteroid-responsive PLE who developed bilateral serous retinal detachments (RDs) coincident with a flare of her enteropathy. With appropriate treatment of the enteropathy, there was resolution of the serous detachments.
Report of a Case
A 47-year-old woman was diagnosed as having idiopathic PLE 8 years before referral to the Retina Service of the Department of Ophthalmology and Visual Sciences, University of Wisconsin–Madison.
In 1995, she was seen at the Mayo Clinic, Rochester, Minn, complaining of swelling over the face and lower extremities. The findings from the physical examination revealed . . . [Full Text of this Article]
Comment
Jayant Venkatramani, MBBS;
Justin L. Gottlieb, MD;
Thom S. Thomassen, MD;
Adamarie Multari, MD
Correspondence: Dr Gottlieb Retina Service, Department of Ophthalmology and Visual Sciences, University of Wisconsin–Madison, 2870 University Ave, Suite 206, Madison, WI 53705 (jlgottlieb@wisc.edu).
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