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Anterior Uveitis and Concurrent Allergic Conjunctivitis Associated With Long-term Use of Topical 0.2% Brimonidine Tartrate
Arch Ophthalmol. 2004;122:1063-1066.
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Brimonidine tartrate is a relatively selective  2-agonist that lowers intraocular pressure by reducing aqueous humor production and by increasing uveoscleral aqueous humor outflow. Ocular side effects associated with brimonidine use include pruritus, as well as follicular conjunctivitis. Recently, 2 reports have described the development of anterior uveitis in 5 patients treated with brimonidine.1-2 Herein we report 4 additional cases of uveitis and concurrent allergic conjunctivitis associated with the use of 0.2% brimonidine tartrate. The 4 cases are summarized in Table 1.
Table appears in full text version.
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Report of Cases
Case 1. An 82-year-old woman sought care from her general ophthalmologist because of redness, blurred vision, and photophobia in her right eye. The patient had a history of glaucoma and had been treated with 0.2% brimonidine tartrate in the right eye during the previous 16 months. Anterior uveitis was diagnosed in the right eye and resolved after a 5-week course of topical 1% prednisolone acetate. . . . [Full Text of this Article]
Comment
Heidi I. Becker, MD;
R. Christopher Walton, MD, MHA;
Jonathan I. Diamant, MD;
Michael E. Zegans, MD
Correspondence: Dr Zegans, Department of Surgery (Ophthalmology) and Department of Microbiology and Immunology, Dartmouth Medical School, 204 Vail Bldg, Hanover, NH 03755-3842.
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ABSTRACT
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