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  Vol. 122 No. 7, July 2004 TABLE OF CONTENTS
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Fish Stories and Clinical Trials

William C. Frayer, MD; William J. Frayer, AB, MSEd

Arch Ophthalmol. 2004;122:1049-1051.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In this era of ever-increasing printed and electronic publications, we often take for granted the accuracy of the information provided. As the meaning of the presentation is debated, we assume that the data on which we base our judgment have been honestly and accurately developed. Occasionally, it is wise to remember that editorial lapses may lead to false conclusions, as the following story will illustrate.

The American Association for the Advancement of Science, along with its weekly publication, Science, had served for more than a century as a dependable public source of scientific information. It was no surprise, therefore, that when an article appeared in the September 12, 1952, issue of the magazine claiming success in the prevention and treatment of cataracts by the administration of fish lens protein, the proposal received widespread attention. Soon, an estimated 1000 volunteers had . . . [Full Text of this Article]

From the Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania Health System, Philadelphia (Dr Frayer); and the Department of Humanities, Central Maine Community College, Auburn (Mr Frayer). The authors have no relevant financial interest in this article.


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