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In the amblyopia treatment article by the Pediatric Eye Disease Investigator Group (PEDIG),¹ the authors state that they "conducted a randomized clinical trial to compare 2 hours vs 6 hours of daily patching for moderate amblyopia" and subsequently reported no difference in the therapeutic outcome. However, patient compliance for the prescribed number of hours of occlusion was not well documented in this study. To determine the effect of 1 treatment variable (number of hours of patching), another variable in the therapy (compliance with the prescribed number of patching hours) cannot be left uncertain.

Compliance problems with patching are well documented in the amblyopia literature and well known by ophthalmologists in their clinical practices.^2-4 Electronic monitors have been used in some studies to assess this problem.^{2, 4-5} The authors of the PEDIG article¹ reported that 63% of the patients who were instructed to patch for 6 hours were noted, by their parents, . . . [Full Text of this Article]

Jeffrey N. Bloom, MD
Chicago, Ill