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Undifferentiated Sinonasal Carcinoma With Nasolacrimal Duct Obstruction
Arch Ophthalmol. 2004;122:290-293.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Sinonasal undifferentiated carcinoma (SNUC) is an uncommon malignancy of the nasal and paranasal sinuses. First recognized by Frierson et al1 in 1986 as a distinct clinical and pathologic entity, it was recently classified as a large cell subtype of poorly differentiated neuroendocrine carcinoma by Mills.2 Common initial symptoms include nasal obstruction, epistaxis, and facial pain.3 Late-stage SNUC may exhibit an orbital mass, causing proptosis, diplopia, and visual loss. Orbital invasion occurs in 59% of nasal and paranasal malignant tumors, occasionally demonstrating dental symptoms.4 We report a case of SNUC in a patient with recurrent dacryocystitis and epiphora.
Report of a Case.
A 71-year-old Chinese woman was first seen in April 1999. Her chief complaints were sudden onset of swelling and pain over the right medial canthal area for 1 week. Her medical history was remarkable for recurrent dacryocystitis with tearing and discharge. The problem had been waxing and waning for 1 year. There was . . . [Full Text of this Article] Comment.
Benedict C. C. Liang, FRCS;
Yuk-Ping Chau, MB, BS;
Dennis S. C. Lam, FRCS, FRCOphth;
Nongnart R. Chan, MD
Hong Kong
Corresponding author and reprints: Nongnart R. Chan, MD, Eye Pathology Laboratory, Department of Ophthalmology and Visual Sciences, Chinese University of Hong Kong, Hong Kong Eye Hospital, 147K Argyle St, Kowloon, Hong Kong (e-mail: nongnart28@hotmail.com).
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