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Long-term Survival in a Patient With Uveal Melanoma and Liver Metastasis
Arch Ophthalmol. 2004;122:285-287.
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Uveal melanoma1 is the most common primary ocular malignancy in whites and represents 70% of all primary ocular malignancies. In patients with metastatic uveal melanoma, the prognosis for those with initial metastasis to the liver is particularly poor. The median survival of patients who first develop liver metastasis from uveal melanoma is 5 to 7 months, as compared with 18 months for other initial sites of metastasis.2-4 This poor prognosis continues despite treatment modalities such as chemoembolization.5-6 We report a case of uveal melanoma with initial metastasis to the liver in a patient who survived for more than 5 years after diagnosis of liver metastasis.
Report of a Case.
Possible uveal melanoma in the left eye was diagnosed in a 74-year-old white woman with a history of hypertension. The melanoma was discovered after she sought evaluation for decreased visual acuity in that eye. The patient was seen at the Wilmer Eye Institute, Baltimore, Md, . . . [Full Text of this Article]
Comment.
Elia J. Duh, MD;
Andrew P. Schachat, MD
Baltimore, Md
Daniel M. Albert, MD;
Sarit M. Patel, MD
Madison, Wis
Corresponding author: Elia J. Duh, MD, 600 N Wolfe St, Jefferson 3-109, Baltimore, MD 21287 (e-mail: eduh@jhmi.edu).
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Pawlik et al.
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ABSTRACT
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Development of Metastatic Disease After Enrollment in the COMS Trials for Treatment of Choroidal Melanoma: Collaborative Ocular Melanoma Study Group Report No. 26
Collaborative Ocular Melanoma Study Group*
Arch Ophthalmol 2005;123:1639-1643.
ABSTRACT
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