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Diagnosis of Microsporidia Keratitis by Polymerase Chain Reaction
Arch Ophthalmol. 2004;122:283-284.
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Report of a Case.
A 33-year-old man positive for human immunodeficiency virus had a 6-month history of bilateral blurred vision, tearing, and photophobia, with associated conjunctival hyperemia. The patient had been previously treated with topical antibiotic drops, topical steroids, and topical nonsteroidal anti-inflammatory drops for several months without resolution of his symptoms. He was taking highly active antiretroviral therapy as well as trimethoprim-sulfamethoxazole prophylaxis; his CD4 cell count was 3. His medical history included weight loss and diarrhea. His ocular history was otherwise unremarkable. His uncorrected visual acuity was 20/70 OD and 20/50 OS with pinhole to 20/50 OD and 20/30 OS. The conjunctiva had 2+ hyperemia with a moderate papillary reaction bilaterally. The corneas exhibited diffusely distributed small, gray intraepithelial lesions without associated stromal infiltrate (Figure 1). There was no anterior chamber reaction, and the posterior segments were unremarkable.
Figure appears in full text version.
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Figure 1. Intraepithelial keratitis in a human immunodeficiency virus–positive patient.
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The patient . . . [Full Text of this Article]
Comment.
Michael S. Conners, MD, PhD;
Terri S. Gibler, BS;
Russell N. Van Gelder, MD, PhD
St Louis, Mo
Corresponding author: Russell N. Van Gelder, MD, PhD, Department of Ophthalmology and Visual Sciences, Washington University Medical School, Campus Box 8096, 660 S Euclid Ave, St Louis, MO 63110 (e-mail: vangelder@vision.wustl.edu).
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ABSTRACT
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