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  Vol. 122 No. 2, February 2004 TABLE OF CONTENTS
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  Clinicopathologic Reports, Case Reports, and Small Case Series
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The Use of Apraclonidine in the Diagnosis of Horner Syndrome in Pediatric Patients

Arch Ophthalmol. 2004;122:276-279.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Horner syndrome refers to a condition where oculosympathetic pathway damage or dysfunction can cause ptosis, miosis of the pupil, and anhydrosis.1 Congenital Horner syndrome is most commonly idiopathic or due to a traumatic birth. Acquired Horner syndrome in children is often postsurgical. Other causes include neuroblastoma, trauma, and brainstem processes.2

The diagnosis of this condition may be confirmed by instilling topical cocaine in each eye. The Horner pupil dilates poorly in comparison with the healthy pupil.3

Apraclonidine hydrochloride is an {alpha}-adrenergic receptor agonist that is approved for the treatment of elevated intraocular pressure following argon laser trabeculoplasty. A prior study4 of 6 adult patients with Horner syndrome showed that instillation of 1% apraclonidine into both eyes produced mydriasis in the affected eye only. In fact, all patients experienced a reversal of their baseline anisocoria. In every case, the miotic pupil on the Horner side dilated to become larger than the . . . [Full Text of this Article]

Report of Cases.


Comment.
Darron A. Bacal, MD
Milford, Conn

Susan R. Levy, MD
Guilford, Conn

Corresponding author and reprints: Darron A. Bacal, MD, Eye Physicians & Surgeons, PC, 202 Cherry St, Milford, CT 06460 (e-mail: kideyedoc2002@yahoo.com).



THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

The sensitivity and specificity of 0.5% apraclonidine in the diagnosis of oculosympathetic paresis
Koc et al.
Br. J. Ophthalmol. 2005;89:1442-1444.
ABSTRACT | FULL TEXT  

The Utility of 0.5% Apraclonidine in the Diagnosis of Horner Syndrome
Brown
Arch Ophthalmol 2005;123:578-578.
FULL TEXT  





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