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Dreams of Canalostomies
Arch Ophthalmol. 2004;122:1868-1869.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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By the early 1970s, trabeculectomy had brought a more predictable outcome than the established full-thickness filtration, but some compromise in the hypotensive response dampened widespread enthusiasm. About a decade later, Zimmerman et a1 modified trabeculectomy by dissecting away the inner wall of the Schlemm canal while preserving the low-resistance corneoscleral component of the trabecular meshwork. Despite initial interest, the nearly simultaneous introduction of antimetabolite adjunctive therapy to conventional trabeculectomy deluged Zimmermans technically daunting procedure with the widely held expectation that antifibrotics would forgive a clumsy technical effort. It became apparent, however, that antimetabolites merely traded lower pressure for more complications, notably hypotony and leaking blebs, which were reminiscent of the full-thickness filtrations from previous decades.
More important, even successful transscleral filtration to the subconjunctival space offers no respite for the need to comply with medications and regular office visits. The eventual freedom from daily instillation of hypotensive medications comes at . . . [Full Text of this Article] AUTHOR INFORMATION
Michael Van Buskirk, MD
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