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Vesicular Eruption in a Child With Trigeminal Nerve Palsy During Topical Therapy With Substance P and Insulinlike Growth Factor I for Neurotrophic Keratitis
Arch Ophthalmol. 2004;122:1722-1723.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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In 1997, Brown et al1 reported on the use of substance P and insulin-like growth factor I for the topical treatment of neurotrophic and anhidrotic keratitis in a child. Since then, other authors have used these compounds2-3 to treat a variety of corneal conditions that caused chronic focal or diffuse epithelial disruption. Herein, we report a possible complication when the combination of substance P and insulinlike growth factor I was used to treat neurotrophic keratitis in a child with complete trigeminal nerve (cranial nerve V) palsy.
Report of a Case
A 28-month-old girl sustained permanent, total left trigeminal nerve palsy after a motor vehicle crash. She was referred to us 3 months later with a chronically red eye and partial ptosis. The mother reported that the child would vigorously rub and pick at her left nostril (causing bleeding), scratch her cheek, and also dig her fingers into her left inferior conjunctival fornix, without evidence . . . [Full Text of this Article] Comment
AUTHOR INFORMATION
Sandra M. Brown, MD;
Arshad M. Khanani, MA;
Cloyce L. Stetson, MD;
Ted W. Reid, PhD
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