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Now That We Have the Results of the Subretinal Surgery Trials, How Do We Manage the Patient?
Arch Ophthalmol. 2004;122:1705-1706.
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In this month’s issue, the Subretinal Surgery Trial (SST) investigators report the outcomes of surgical removal of subfoveal choroidal neovascularization (CNV) compared with a control group of patients with the ocular histoplasmosis syndrome (OHS) and with idiopathic CNV.1-2 The goal of the SST was to answer the question of whether surgery offered a benefit over the often unfavorable natural history of the disease. Previously published studies showed promise for a surgical approach,3-5 but these studies had no concurrent controls without surgery to determine if the outcomes were better than the natural history and had limited follow-up to determine if such outcomes were sustained.
Sponsored by the National Eye Institute, the SST was a randomized prospective clinical trial conducted by retina-trained physician investigators, supporting ancillary personnel (coordinators, vision examiners, and photographers) at various medical centers, a coordinating center, and photograph reading center. The SST protocol contained strict eligibility criteria, photographic documentation . . . [Full Text of this Article]
AUTHOR INFORMATION
Harry W. Flynn, Jr, MD;
Ingrid U. Scott, MD, MPH
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Surgical Removal vs Observation for Subfoveal Choroidal Neovascularization, Either Associated With the Ocular Histoplasmosis Syndrome or Idiopathic: I. Ophthalmic Findings From a Randomized Clinical Trial: Submacular Surgery Trials (SST) Group H Trial: SST Report No. 9
Submacular Surgery Trials Research Group
Arch Ophthalmol. 2004;122(11):1597-1611.
ABSTRACT
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Surgical Removal vs Observation for Subfoveal Choroidal Neovascularization, Either Associated With the Ocular Histoplasmosis Syndrome or Idiopathic: II. Quality-of-Life Findings From a Randomized Clinical Trial: SST Group H Trial: SST Report No. 10
Submacular Surgery Trials Research Group
Arch Ophthalmol. 2004;122(11):1616-1628.
ABSTRACT
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