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Arch Ophthalmol. 2004;122:1551-1555.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Juvenile xanthogranuloma (JXG) is a rare idiopathic granulomatous disorder of early childhood. Ocular involvement of the anterior segment, notably the iris, is well recognized. Involvement of the optic nerve disc is exceptionally rare and is associated with loss of vision. We are aware of only 2 previously published reports of optic disc involvement, one proven on histologic examination¹ and the other presumed.² We describe herein a third child who was initially identified by screening and in whom it was possible to detect early optic disc involvement. As far as we know, we describe for the first time the prospective clinical management of this vision-threatening condition during more than 2 years of follow-up. This case illustrates the natural history of this condition and demonstrates that vision can be partly preserved with early detection and treatment.

Report of a Case

A previously healthy 11-month-old white girl was referred to the pediatric dermatology department with a 5-month . . . [Full Text of this Article]

Comment
Göran Darius Hildebrand, MD, MRCOphth, MRCS(Edin); Chris Timms, DBO(T); Dorothy A. Thompson, PhD; David J. Atherton, FRCP; Marian Malone, FRCPath; Gill Levitt, FRCP; D. Alistair H. Laidlaw, FRCOphth; Isabelle Russell-Eggitt, FRCOphth; David S. I. Taylor, FRCP, FRCS, FRCOphth

Correspondence: Dr Taylor, Department of Paediatric Ophthalmology, Great Ormond Street Hospital for Children, London WC1N 3JH, England (DSIT@btinternet.com).