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Acute Severe Vision Decrease Immediately After Photodynamic Therapy
Arch Ophthalmol. 2004;122:1546-1547.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Ocular photodynamic therapy (PDT) with verteporfin has been shown to be an effective treatment for occult subfoveal choroidal new vessels (CNV) in age-related macular degeneration, but is associated with acute severe vision decrease (ASVD) in 4.4% in patients who received the treatment.1
In this case the patient complained of decreased vision within hours of treatment, affording the opportunity to examine and assess the mechanism of vision loss 4 hours after therapy.
Report of a Case
An 82-year-old female patient had a sudden decrease in visual acuity. On examination, her acuity had decreased from 20/30 to 20/40 OU and her fundus showed a mild mottling of the pigment epithelium and no evidence of hemorrhage or exudative abnormalities. Fluorescein angiography showed an occult subfoveal CNV of 2.5 disc areas in size (Figure 1). On the basis of recent disease progression2 and small lesion size she was treated with PDT. Following infusion of verteporfin (6 . . . [Full Text of this Article] Comment
Paul Beaumont, FRANZCO;
Charmaine S. Lim;
Andrew Chang, FRANZCO;
Kwon Kang, MBBS
Correspondence: Dr Beaumont, 13th Floor, 187 Macquarie St, Sydney NSW 2000, Australia (pbeau@ozemail.com.au).
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