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Is Coxsackievirus the Cause of Unilateral Acute Idiopathic Maculopathy?
Arch Ophthalmol. 2004;122:121-123.
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Unilateral acute idiopathic maculopathy (UAIM) is an inflammatory process involving the outer retina and retinal pigment epithelium (RPE) of the macula. It is typically associated with a serous neurosensory detachment and is sometimes associated with papillitis, subretinal exudation, intraretinal hemorrhages, and/or vitreous cells.1-2 Patients report a loss of central vision followed by a remarkable spontaneous recovery over a period of several weeks. This entity frequently affects young, healthy individuals and is often associated with a prodromal flulike illness. We describe 2 patients who developed ocular findings consistent with UAIM shortly after developing classic signs and symptoms of hand-foot-and-mouth disease. We believe that coxsackievirus, which causes hand-foot-and-mouth disease, may also cause UAIM.
Report of Cases
Case 1
A 30-year-old woman had a 5-day history of decreased vision in her left eye. Hand-foot-and-mouth disease had spread through her child's daycare center that same week. The patient had a sore throat and small erythematous papules on the palms . . . [Full Text of this Article] Case 2 Comment
Adam P. Beck, MD;
Lee M. Jampol, MD
Chicago, Ill
David A. Glasser, MD
Florissant, Mo
John S. Pollack, MD
Chicago
Corresponding author and reprints: Lee M. Jampol, MD, Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, 645 N Michigan Ave, Suite 440, Chicago, IL 60611 (e-mail: L-jampol@northwestern.edu).
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